The quadruple marker test (or quad screen) is a maternal blood test performed between 15-20 weeks of pregnancy. The Quadruple Marker Test is a screening tool taken to help calculate the risk of certain genetic conditions in the infant. The quadruple marker test tests for the presence of four substances in the mother's blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), estriol, and inhibin A. Each of these markers are used in calculating risk of Down Syndrome, Edwards Syndrome, and some neural tube defects. The quad screen is a simple and uncomplicated screening process that only requires a small blood draw or sample. The maternal serum report is interpreted in conjunction with other risk factors, including maternal age, maternal weight, and gestation age.
For example, if everything is within normal limits, that indicates the expectant mother is experiencing low risk for certain conditions. There can still be some abnormalities, but low risk simply is not definitive that there will be a condition. High risk does not mean the expectant mother is confirmed to have a condition- just that her physician may recommend further diagnostic tests to confirm a condition. The best IVF Clinics in Chennai, such as Dr. Aravind IVF, offer state-of-the-art laboratories, highly trained embryologists, and highly experienced doctors; their doctors will develop an individualized patient plan for each couple. Finally, a quadruple marker test done in pregnancy is helpful for parents and health care workers and provides an opportunity for them to make informed decisions regarding genetic counseling and control of fetal medical treatment and comfort.
The quadruple marker test simplified as quad test and also measures four substances that are specific to the mother's blood.
The baby's genetic disorders and neural tube anomalies by examining these molecules Doctors can quickly identify. The Quadruple Marker test in pregnancy is most recommended for women in their 15th and 20th weeks of gestation, with 16–18 weeks being the most accurate period.
The procedure itself is simple and carries no harm to the infant. The mother's arm is used to obtain a blood sample. The sample is drawn in a diagnostic lab or hospital, and here's what the procedure looks like:
If the Quadruple Marker Test Normal Report indicates higher than normal risk, it does not determine the baby has the condition. It simply indicates more diagnostic tests may be needed. This is why it is important to go over the results with the best IVF clinics or a qualified obstetrician.
The quadruple marker test detects risk for these conditions.
The quadruple marker test calculates the likelihood that a child will have Down syndrome. Then if the estimation indicates an increased risk, a follow-up test to confirm (e.g. amniocentesis or chorionic villus sampling (CVS)) will be recommended. Stop for a moment! We need to better understand the Down Syndrome Definition before moving forward. An extra chromosome is the cause of the genetic disease known as Down syndrome. It is associated with developmental delay, as well as recognizable physical characteristics, and in some cases there are heart defects.
One additional copy of chromosome 18 (or part of it) is involved in the rare but dangerous genetic disorder known as Edward Edwards syndrome (Trisomy 18), which disrupts normal growth and ultimately results in a variety of health and developmental issues. At least in terms of the number of incidents that have been found, Edwards syndrome is uncommon. One out of every five thousand live babies has Edwards syndrome. As people age, the likelihood of giving birth to a child with Edwards syndrome rises. Infants born with Edwards syndrome will usually demonstrate classic characteristics and clinical issues.
Some of the characteristics associated with Edwards Syndrome Symptoms include low birth weight, microcephaly, clenched hands with overlapping fingers, hypoplastic jaw, congenital heart defects, kidney defects, and feeding issues. Most infants will also demonstrate significant global developmental delay. Sadly, when Edwards syndrome occurs, there is a high likelihood of miscarriage or stillbirth, and most infants born will have significant medical issues or require surgical intervention with a generally poor prognosis. While there is no therapeutic intervention for Edwards syndrome, confirming the syndrome during the prenatal period using prenatal screening, including quadruple marker tests and detailed ultrasound, may prepare parents, both emotionally and medically, for a child with Edwards syndrome and potentially provide less obstruction to accessing medical care and support systems.
If your quadruple marker test results indicate an increased risk for Down syndrome, Edwards syndrome, or neural tube defects, your doctor may want to consider:Full ultrasound scans to determine structural defects. An amniocentesis that looks directly at the baby’s chromosomes. Genetic counseling to be informed of the results and what they may mean. This is where the Best IVF Doctor or maternal-fetal medicine specialist can be of great value at Dr. Aravind’s IVF fertility center. They will explain the risks clearly and help parents understand the next steps in a thoughtful way.
There is no doubt that patients who come to Dr. Aravind IVF for assistance will have the highest chance of achieving a successful and healthy pregnancy. In addition to IVF treatment plans, many clinics offer related services such as genetic testing and counseling support and donor programs and are concerned about your emotional well-being. For couples who are suffering from blocked fallopian tubes, severe male infertility, or unexplained infertility, there is hope with the use of advanced technology and clinically caring professionals such as those at Dr. Aravind IVF.
The quadruple marker test (or quad screen) is a maternal blood test performed between 15-20 weeks of pregnancy. The quadruple marker test is a screening tool taken to help calculate the risk of certain genetic conditions in the infant.
The best week to take the four-part marker test is from week 15 to week 20 of being with a child. It works best in the second set of weeks. Taking a quadruple test early leads to wrong results.
Down syndrome can lead to a slow mind, unique face looks, and heart troubles. Edwards syndrome hits harder, causing slow growth, organ issues, and lower chances of living.
The checking process needs a small blood sample from the mother. No need to fast or get ready in a certain way. They test the blood to look at four key signs. You can get the results in just a couple of days.
Down syndrome can't be fully stopped, as it is tied to genes. Early tests while pregnant, like the NT scan and marker tests, help spot it early. the risks may go down if a woman gets pregnant before age 35.
