What is the Double Marker Test?
The double marker test, also known as maternal serum screening, is a blood test that measures
two specific markers in your blood: beta-human chorionic gonadotropin (hCG) and
pregnancy-associated plasma protein A (PAPP-A). Both of these markers are produced during
pregnancy, and their levels can indicate the chances of chromosomal disorders in the fetus.
1. Why is the Test Important?
Chromosomal abnormalities can lead to conditions such as Down syndrome (trisomy 21),
Edwards's syndrome (trisomy 18), and Patau's syndrome (trisomy 13). These conditions can
result in developmental delays and various health challenges for the baby. The double marker
test helps identify these risks early in the pregnancy, allowing for better planning and
decision-making for parents.
2.When Should the Test be Performed?
The double marker test is usually performed between the 8th and 14th weeks of pregnancy, with
blood samples ideally collected between the 11th and 13th weeks. This timeframe is crucial for
accurate measurement of hormone levels when they are most relevant for risk assessment.
Doctors often recommend this test for women over 35 or those with a family history of genetic
disorders.
3.How Does the Test Work?
The process starts with a simple blood draw. After your blood is taken, it’s analyzed to measure
the levels of hCG and PAPP-A. Along with this blood test, an ultrasound known as a nuchal
translucency (NT) scan may be conducted. The NT scan measures the fluid at the back of the
baby’s neck, providing additional information that helps assess the risk of chromosomal
disorders.
4.Benefits of the Double Marker Test
One significant benefit of the double marker test is early detection. Knowing about potential
risks allows parents to prepare for any challenges and make informed choices regarding their
pregnancy. This test provides peace of mind and helps families plan for the future.
5.Costs and Accessibility
The cost of the double marker test typically ranges from 2500 to 3500 INR, depending on the
location and healthcare facility. Many hospitals and clinics offer this test, making it accessible for
expectant parents.