What Does a Double Marker Test Tell About Pregnancy?

What is the Double Marker Test?

The double marker test, also known as maternal serum screening, is a blood test that measures

two specific markers in your blood: beta-human chorionic gonadotropin (hCG) and

pregnancy-associated plasma protein A (PAPP-A). Both of these markers are produced during

pregnancy, and their levels can indicate the chances of chromosomal disorders in the fetus.

1. Why is the Test Important?

Chromosomal abnormalities can lead to conditions such as Down syndrome (trisomy 21),

Edwards's syndrome (trisomy 18), and Patau's syndrome (trisomy 13). These conditions can

result in developmental delays and various health challenges for the baby. The double marker

test helps identify these risks early in the pregnancy, allowing for better planning and

decision-making for parents.

2.When Should the Test be Performed?

The double marker test is usually performed between the 8th and 14th weeks of pregnancy, with

blood samples ideally collected between the 11th and 13th weeks. This timeframe is crucial for

accurate measurement of hormone levels when they are most relevant for risk assessment.

Doctors often recommend this test for women over 35 or those with a family history of genetic

disorders.

3.How Does the Test Work?

The process starts with a simple blood draw. After your blood is taken, it’s analyzed to measure

the levels of hCG and PAPP-A. Along with this blood test, an ultrasound known as a nuchal

translucency (NT) scan may be conducted. The NT scan measures the fluid at the back of the

baby’s neck, providing additional information that helps assess the risk of chromosomal

disorders.

4.Benefits of the Double Marker Test

One significant benefit of the double marker test is early detection. Knowing about potential

risks allows parents to prepare for any challenges and make informed choices regarding their

pregnancy. This test provides peace of mind and helps families plan for the future.
5.Costs and Accessibility

The cost of the double marker test typically ranges from 2500 to 3500 INR, depending on the

location and healthcare facility. Many hospitals and clinics offer this test, making it accessible for

expectant parents.



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