Our Treatments

Paternal Lymphocyte Immunization (PLI) is a treatment used in infertility care, especially for couples struggling with recurrent miscarriages or pregnancy loss due to immune system problems.

Sometimes, the mother’s immune system may see the developing baby (made from both the mother’s and father’s genes) as foreign and attack it. PLI helps the mother's body "get used to" the father's genetic material so the pregnancy can continue successfully.

Our Procedure for Paternal Lymphocyte Immunization (PLI) Will Include:

• A small amount of blood is taken from the husband (or sperm donor if applicable).
• The white blood cells called lymphocytes are separated from the blood. These cells are processed into a concentrated solution.
• The prepared lymphocyte solution is injected into the wife's forearm using shallow injections.The injections are painless and quick.
• A second set of injections is done after 3–4 weeks to strengthen the immune response.
• The couple is advised to wait for about 4 weeks after the injections before trying to conceive.
• Doctors will check the results and decide if a booster injection is required.

FAQs

1. What is PLI?

    Paternal Lymphocyte Immunization (PLI) helps the mother's immune system accept the father's genetic material to support a successful pregnancy.

2. Are the injections in PLI painful?

    No, the injections are painless and quick.

3. How long does the PLI procedure take?

    The injections are fast, and the entire procedure typically takes just a few minutes.

4. How many injections are required?

    The first set of injections is followed by a second set after 3–4 weeks.

5. When can the couple try to conceive?

    The couple is advised to wait 4 weeks after the injections before trying to conceive.

6. Does PLI require a booster injection?

    A booster injection may be required depending on the results, as determined by the doctor.

7. Is PLI effective?

    PLI can be highly effective for couples dealing with immune system-related infertility issues, especially recurrent miscarriage.